KYM- Know Your Medicine

Spasmodic Pain: Causes, Mechanism & Treatment Spasmodic Pain: Causes, Mechanism & Treatment Spasmodic pain is also known as smooth muscle pain or visceral pain. It occurs due to excessive contraction of smooth muscles, especially in hollow organs of the body. 📌 Introduction When smooth muscles of hollow visceral organs contract abnormally, they stimulate pain fibers and cause discomfort. This type of pain is commonly called colic . G.I. Colic: Stomach & intestine Renal Colic: Kidney Biliary Colic: Bile duct Ureteric Colic: Ureters Uterine Colic: Uterus 📍 Site of Occurrence Smooth muscles of hollow visceral organs. ⚡ Stimulus Mechanical in nature. ⚙️ Mechanism of Spasmodic Pain Mechanical stimulus activates parasympathetic nerves Increased release of Acetylcholine (ACh) ACh binds with M1 muscarinic receptors Leads to excessive smooth muscle contraction Results in spasm (colic) and pain Importan...

  🩺 Pain – Definition, Types & Mechanism (Easy Notes) What is Pain? Pain is one of the most common clinical symptoms of a disease. It is an unpleasant and subjective experience that occurs when body tissues are damaged. Pain acts as a protective reflex, helping the body react and remove harmful stimuli. Pain Centre The pain centre is located in the cerebral cortex and hypothalamus of the brain. Pain Receptors Pain is sensed through receptors. Free nerve endings act as pain receptors and are present throughout the body. These receptors respond to three types of stimuli: Mechanical Thermal Chemical Pain Pathway When pain receptors are stimulated, signals are transmitted to the brain’s pain centre, where the sensation of pain is perceived. Classification of Pain Pain can be classified as: Acute pain Chronic pain Based on origin: Skeletomuscular (Inflammatory) pain Smooth muscle (Spasmodic) pain Difference Between Pain Types Spasmodic Pain: Occurs...